Full and partial remote work options are available with hiring manager approval. Periodic travel to Farmington and/or Bar Harbor campuses expected in the future.
The Jackson Laboratory (JAX) is seeking a computational biologist to join a single-cell imaging and informatics team embedded within the Computational Sciences group. The successful candidate will apply statistical, machine learning, and deep learning approaches to predict phenotypes in cancer and non-malignant disease from imaging and spatial expression data generated by cutting-edge technologies within JAX's Single Cell Biology Laboratory (SCBL). These platforms include spatial transcriptomics, which provides unbiased, spatially-resolved expression profiles of mixtures of cells, and imaging mass cytometry (IMC), which affords a highly multiplexed (~40 proteins) perspective of individual cells. SCBL's platforms continue to evolve and will soon include CODEX and multiplex FISH. The primary responsibilities of the... Computational Scientist involve providing analysis of tissue imaging data and interpreting their results across a range of biological and translational domains. The Computational Scientist will apply and optimize published methods and pipelines when they exist and develop novel methods when they do not. In doing so, they will accelerate adoption of advanced imaging and spatially-aware technologies at JAX.
The Computational Scientist will stay current in the latest image analysis methods and their biological application by attending and presenting at conferences. They will expand their professional network through collaborations with faculty across JAX campuses and with external investigators and consortia (e.g., PDXNet). Finally, they will have significant growth opportunities to develop novel and evaluate existing methods in the rapidly evolving field of highly multiplexed image analysis and to deploy them in advancing biological discoveries.
A Successful Computational Scientist will have:
Characteristic distinction from Assistant to Full Computational Scientist includes increased ability to work independently, liaise directly with biologists, develop in-depth knowledge in selected biological disciplines, provide biological interpretation of results, contribute to or lead grant submissions, and mentor more junior Computational Scientists.
The ideal candidate will have one or more of the following:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws